Systems /
iScan
iScan
Applications: SNP Genotyping and CNV Analysis, Custom Genotyping, Cytogenetic Analysis, Focused Genotyping, Linkage Analysis, Whole-Genome Genotyping and Copy Number Analysis, Gene Regulation and Epigenetic Analysis, Array-Based Methylation Analysis, Gene Expression Analysis, Array-Based Transcriptome Analysis, FFPE Sample Analysis, Whole-Genome Gene Expression Analysis
The iScan System is a cutting-edge, high-resolution, scanner that supports rapid, sensitive, and accurate imaging of Illumina's array-based genetic analysis products. The system features a high signal-to-noise ratio, high sensitivity, an excellent limit of detection, and a broad dynamic range leading to exceptionally high data quality. More...
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System Description
At the System's core is the iScan Reader, which incorporates high-performance lasers, optics, and detection systems. The iScan Reader offers sub-micron resolution and unmatched throughput rates. Even the highest density BeadChips can be scanned in just minutes, allowing processing of up to 96 mulit-sample BeadChips per day.
- These imaging features are especially beneficial for high-density genotyping, CNV analysis, DNA methylation, and gene expression profiling
- The iScan System supports Infinium, GoldenGate, DASL, Gene Expression (Direct Hybridization), and Methylation assays along with different multi-sample BeadChip formats
The iScan System includes a computer workstation to control all aspects of the scanner. This automated system provides laser control, precision mechanics control (including focus motor), detection of excitation signals, image registration, image extraction, and data output. Data analysis is supported by GenomeStudio software featuring easy-to-use visualization tools, advanced data manipulation features, and extensive reporting capabilities.
- The iScan Reader can be built-out with LIMS (laboratory information management system) and assay automation options to streamline sample tracking and workflow management for large-scale projects
- An AutoLoader2 can be added to either single- or dual-scanner systems to maximize throughput to thousands of samples per day
Speed. Quality. Versatility.
Empower your research with a revolutionary high-precision scanner that supports an extensive range of applications from microarrays to sequencing, unlocking the potential for limitless discovery.
Latest Publication
Workflow & Specs
iScan provides a streamlined imaging detection workflow that requires minimal user interaction through automated scanning setup and data processing. The optional robotic Autoloader2 and Laboratory Information Management System allow you to further increase throughput and avoid costly handling errors.
Assays/Protocols
BeadArray: Infinium HD, Infinium Methylation, DASL, Direct Hyb
| iScan Specifications | |
|---|---|
| Field of View | 1 mm wide |
| Pixel Resolution | 0.54 micron |
| Laser Excitation | 532 nm and 658 nm dual-laser excitation |
| Emission Spectra | 550-600 nm and 677-697 nm |
| Image Registration | Automatic |
| Data Extraction | Automatic |
| Image File Output | TIFF, PNG, or JPG data file output with automatic image quality analysis (uncompressed or compressed) |
| Data File Output | IDAT (Illumina proprietary format) |
| Detector Analog-to-Digital Converter | 16-bit |
| Limit of Detection | 5 fluor/µm2 (Cy3 or Cy5) |
| Input Voltage | 100-240V AC 50/60 Hz, single phase |
| Input Power | 3A (110V); 1.5A (220V) |
| Dimensions | 52 cm (width) × 45 cm (height) × 66 cm (depth) |
| Dimensions of Air Table | 61 cm (width) × 6 cm (height) × 69 cm (depth) |
| Weight | 65 kg |
Module
AutoLoader2
Automation Option Packages
- GoldenGate Genotyping Automation Upgrade Kit
- GoldenGate Genotyping and Infinium Automation
- GoldenGate Genotyping and Infinium Automation Illumina LIMS-ready
- Infinium Automation Upgrade Kit
Illumina LIMS
Option Packages
Option Packages (continued)
General Hardware and Accessories
- Storage Boxes
- BeadChip Wash Rack and Glass Tray
- Hybridization Oven
- Tecan Replacement Probes
- Tip Depth Gauge
- GoldenGate Accessory Package
- GoldenGate Accessory Package Plus
- GoldenGate Satellite Option Kit
- Infinium Alignment Fixture
- Infinium BeadChip Expansion Package
- Infinium Hybridization Chambers and Gaskets
- Infinium Staining Set
- Infinium TeFlow Chambers
- Infinium TeFlow Thermometer Assembly
- MIDI Heat Block Insert
Software
Illumina proudly offers system and analysis software designed to maximize your data quality and throughput level. Each instrument includes system control software designed for optimal performance. Data can be analyzed using Illumina's user-friendly GenomeStudio software or a third-party package.
Documentation
- iScan and AutoLoader2 System Guide
- AutoLoader2 Quick Reference Card
- iScan System Quick Reference Card
Literature
Videos
Support
Illumina's Customer Solutions Team is dedicated to providing you with the resources you need to support your research. Scientists specializing in Illumina's technologies, scientific applications, software, and hardware systems are available even before your first system purchase. Field Service Engineers expertly install and qualify your instrument to guarantee a fully functional system. Field Application Scientists offer extensive training, enabling labs to quickly become proficient at generating industry-leading data quality at unparalleled throughput levels. Technical Support Scientists are just a phone call or email away and can help you plan your project, diagnose a problem, and interpret results.
We strive to continuously exceed your expectations, so that you can maximize the impact of Illumina technology in your lab. For more information, visit our Support section