Quantify in vivo protein-DNA interactions using the combination of chromatin immunoprecipitation with Illumina Sequencing technology (ChIP-Seq) on a genome-wide scale. Sequencing millions of ChIP-enriched DNA fragments using the Genome Analyzer enables cost-effective and precise analysis of the binding sites of transcription factors, replication and transcriptional machinery, structural proteins such as histones, as well as of the impact of protein modifications on genome occupancy.

Protein-nucleic acid interactions highlights

 

• Open Platform: Study any immunoprecipitate from any organism with a sequenced genome without any prior assumptions

 

 

• Comprehensive Access: Map in vivo binding sites across the entire genome

 

 

• Cost-Effective Analysis: One-tenth to One-thirtieth the cost of whole-genome ChIP-chip

 

 

• Robust and Precise Detection: Obtain higher signal-to-noise ratios than array platforms; map binding sites less than 50 bp

 

 

• Optimized Kits: Accelerate whole-genome protein-nucleic acid interaction analysis with Illumina's easy-to-use protocols and analysis tools